Some limited studies have shown when coadministering pravastatin with cholestyramine (bile-binding resin), the drug may decrease LDL levels to half and further slow the progression of atherosclerosis and reduce the risk of coronary death. I am pre-diabetic and am using diet and exercise to lose weight albeit with moderate success. I am disturbed to read of the potential relationship between statins and diabetes. Reducing my A1C value has been a struggle and I wonder if I’m battling my statin in this regard. Tests can include blood tests to check how well your liver and kidneys are working, and your cholesterol levels. The cost of these tests will depend on your insurance coverage.
There may be an increased risk of muscle pain in those who are over 65 years old or who have uncontrolled hypothyroidism or kidney problems. The most common side effects of pravastatin are musculoskeletal or muscle pain, nausea, vomiting, diarrhea, and headache. The most common side effects of atorvastatin reviews for neckrelax are musculoskeletal or muscle pain, diarrhea, and joint pain . Both pravastatin and atorvastatin can also cause other side effects such as indigestion, dizziness, fatigue, rash, and urinary tract infections. Both pravastatin and atorvastatin are effective medications for treating high blood cholesterol.
Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions. Before approving coverage for pravastatin, your insurance company may require you to get prior authorization.
They might also prescribe a different statin drug such as Zocor or Crestor . However, people ages 65 years and older may have a higher risk for muscle weakness while taking pravastatin. For this reason, your doctor may take extra precautions before prescribing pravastatin if you’re over age 65. They may also decide to try a different medication to treat your condition. A liver enzyme test can help your doctor determine if pravastatin is causing liver damage, a rare side effect of the drug. Testing your cholesterol levels helps your doctor determine how well the drug is working.
SMV also limits osteoclast activity, while stimulating the formation of bone. The effects of SMV on osteoclast activity and bone formation would seem to suggest that its action is exerted by regulating the ratio of local osteoprotegerin to RANKL in periodontal tissue. Therefore, it has been suggested that SMV might be useful for tooth retention . The effect of local administration of simvastatin on post-treatment relapse was evaluated on 10 rabbits . The combined effect of statin and alpha-tricalcium phosphate (alpha-TCP) on odontoblastic differentiation of human dental pulp cells and its comparison with mineral trioxide aggregate were investigated in one study. The results suggested that alpha-TCP may be used for the local delivery of simvastatin as a pulp capping material to hasten the formation of reparative dentin.